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These drugs can be given as single drug preparations or fixed dose combinations (FDCs) of two more drugs in a single formulation.
However, it was not found in previous works to use carbon nanotubes as single drug to therapy in clinical application, no works could prove that the carbon nanotubes can improve biological function of animals, and most papers only pay attention to toxicology of carbon nanotubes on tissues or cell [5 12].
Secondly, the effect of LBH589 as single drug treatment (continuous treatment) was determined on the in vivo tumor burden.
We previously demonstrated that HDACi as single drug can rescue myeloid maturation in AML cells.
In contrast, Epirubicine was applied as single drug in the ETC therapy of breast cancer patients.
Sorafenib was investigated as single drug and in combination with conventional cytostatics cytarabine and doxorubicin.
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They can be considered as single drugs for the treatment of migraine in particular clinical settings (i.e. emergency department).
Exemestane, the irreversible steroidal aromatase inhibitor, and fulvestrant, the pure estrogen antagonist, are active as single drugs in postmenopausal women with advanced hormone-responsive breast cancer.
This contrasts with the 100% viability of rats that received MINO or cyclosporine as single drugs.
When dosed 3 hours before injury, MINO plus NAC as single drugs had no effect on interleukin-1 formation; together they synergistically lowered interleukin-1 levels.
Surprisingly, when dosed 3 hours prior to injury, neither MINO nor NAC as single drugs blocked the IL-1β increase despite their efficacy as a combination (post-hoc, p = 0.6).
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