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The only previous genomewide scan for linkage to longevity was conducted in part by a member of our group (LMK) and identified a region on chromosome 4q22-25 asignificantlylinkedked in 137 sibships of centenarians and nonagenarians [24].
This set included SRPX2, as significantly linked to poor glioblastoma prognosis (t-test p-value 0.024).
The methodologies in this paper are validated in the identification of specific stable pathway markers (see below) which differentiate cancer phenotypes and validate previous studies identifying the same pathways and their component genes as significantly linked to cancer.
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Occurrences of high groundwater As are significantly linked with the Pleistocene and Holocene aquifers in the Red River Delta and Bengal Delta (Berg et al. 2001; Ravenscroft et al. 2009; Shamsudduha et al. 2008).
Based on visual inspection and comparing the results from the 16 and 17% pool allowed them to predict six loci as being significantly linked to the phenotype, all of which were also explicitly mentioned in the paper.
These studies highlight adolescent and young adults' sexual experiences as being significantly linked to sexual self-concepts that denote sexual assertiveness, agency, arousability, adventure and drive [ 22, 23, 25].
Here we found that both cytoplasmic as well as nuclear RelA/p65 positivity was significantly linked with the expression of specific HDAC isoforms, the strength of those correlations were weak to moderate.
However, his persistence, scholarship and ability to communicate complex ideas in an engaging way resulted in the phenomenon of religious experience being recognised as widely prevalent and significantly linked with psychological wellbeing.
Four biochemical parameters represented by glycemia, fibrinogen, fetuin-A, and TNF- α as well as smoking, CAD, and antihypertensive therapy proved significantly linked with PAD (see Table 4).
In women, sexual abuse was significantly linked to lifetime cocaine (P<.001) as well as marijuana exposure (P<.01).
Radiotherapy, as compared to chemotherapy, was significantly linked to lower satisfaction scores in most scales.
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