Sentence examples for as significant alterations from inspiring English sources

Log2 ratio reaching at least ±0.85 and p < 0.05 were considered as significant alterations aRGD: rat genome database bnon significant change (p > 0.05) Values show gene expression.

The amount of circulating DCP is related to immune status as significant alterations in blood DCP subsets have been demonstrated in a variety of clinical conditions.

Log2 ratio reaching at least ±0.85 and p < 0.05 were considered as significant alterations aRGD: rat genome database bnon significant change (p > 0.05) To determine genes associated with the effects of MVT-treatment in healthy control hearts, cardiac gene expression induced in the control MVT-treated group was compared with the control vehicle-treated group (Tables  6 and 7).

Log2 ratio reaching at least ±0.85 and p < 0.05 were considered as significant alterations aRGD: rat genome database bnon significant change (p > 0.05) To determine genes associated with the effects of MVT-treatment in diabetic hearts, cardiac gene expression induced in the diabetic MVT-treated group was compared with the diabetic vehicle-treated group (Tables  4 and 5).

Nevertheless, biological clues from laboratory [ 13- 19] and in vivo pre-clinical studies [ 20- 23], as well as significant alterations in lipid profile of BC patients compared to healthy controls [ 41- 49],56,[ 57],62,63], are very suggestive for a role of cholesterol in BC progression.

Data were sorted based on "fold change," and genes with at least 1.5-fold up-regulation or down-regulation were accepted as significant alteration and the genes have a significant differential expression in at least four of five experiments chosen for further consideration.

The read density plot (Fig. 7A) and heat map (Fig. 7B) analysis of DGE data showed meal specific restricted expression of unique tags to sugar (12%) or blood feeding (10%) as well as significant alteration of 17% tags (P≤0.05) in response to differential feeding (supplementary material Table S5).

However, disease duration, therapy, or both seem to impact the circulating naïve B-cell pool, as no significant alterations or decreased frequencies are observed in patients with established disease treated with either synthetic or biological disease modifying antirheumatic drugs (DMARDs) [ 53, 55, 56].

We then verified the human microarray data by real-time quantitative RT-PCR analyses (primers shown in see Supplementary Table S1) of 10 genes showing significant alterations as well as PCSK2 and PCSK5– 7 in the hippocampus (see Supplementary Table S8).

Its development control is primarily an open loop process, together with the closed loop process occasionally operating as a complement; significant alterations need to be avoided during the construction.  .

As expected, no significant alterations in secondary structures were detected in CORE and NMP domain during the large-scale conformational transitions.