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Preventing asthma among sensitized children is warranted, as sensitization is a strong risk factor for persistence of asthma in adolescence [ 22, 23].
Recently, Maycotte et al. reported that CQ could sensitize breast cancer cells to chemotherapy independent of autophagy inhibition, as sensitization was not mimicked by Atg12, Beclin 1 knockdown or bafilomycin A1 treatment, and occurred even in the absence of Atg12.
Repeated cocaine exposure causes flies to become increasingly sensitive to the behavioral effects of the drug, a process referred to as sensitization (McClung and Hirsh 1998).
IgE locks onto immune cells (mast cells in tissue and basophils in blood) to prepare for the next encounter with the allergen — a process known as sensitization.
Before generalizing this finding, more compounds as well as sensitization to perennial allergens need to be investigated.
Pharmaceutical drugs and compounds used for consumer products may bear the risk of unexpected immuno-toxicological side effects, such as sensitization, allergy, anaphylaxis or immunogenicity.
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This was done to determine whether MDMA can elicit behavioral sensitization as well as to cross-sensitize with other psychostimulants.
This phenomenon is dependent on stimulus frequency (⩾0.33 Hz) and relevant for central sensitization as well as chronic pain.
Using traditional learning paradigms, evidence suggests that spinal neurons support habituation and sensitization as well as Pavlovian and instrumental conditioning.
RGS9 knockout (KO) mice show increased psychostimulant-induced behavioral sensitization, as well as exhibit higher body weights and greater fat accumulation compared to wild-type (WT) littermates.
Activation of microglia and astrocytes contribute to spinal neuroinflammation [40, 41] and accelerate central sensitization, as well as development and maintenance of neuropathic pain [11, 12].
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