Because the effect of some ubiquinone analogs depends on the cell line, we propose that the affinity of these sites for one particular quinone, as well as the secondary changes in the PTP Ca2+ binding affinity, may change according to the cell line.
The signal representing primary tumor was noted significantly differed from that of secondary atelectasis and pneumonia (i.e., tumor manifested as hypointensity, whereas secondary changes presented as hyperintensity) on early phase of dynamic contrast-enhanced MRI.
Consistent with the definition of AD onset, the same preventive intervention can be labeled as primary when dealing with clinical symptoms only or as secondary if prior pathological changes are considered.
For instance, a chemical that induces inflammation as its primary effect might also induce secondary changes, such as metaplasia (an adaptive shift from one cell type to another) or necrosis (tissue death).
Good PR is characterized as a secondary change unique to post CRT that is regarded as remaining scar but not residual tumor.
Such an effect can lead to a vast amount of secondary changes as Ca2+ itself is a second messenger that controls cellular life and death.
Trisomy 8 has been shown to occur as a secondary change to primary inversions of other chromosomes (i.e., chromosomes 9 and 11) (Paulsson and Johansson, 2007 ).
Histology may show secondary changes, such as aneurysmal-bone cyst-like features, or extensive myxoid changes; there is no nuclear atypia and mitoses are rare [18].
