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Research on the response to LPS in human monocytes and dendritic cells confirmed an increase in the TLR signaling response with age as responsiveness of infants increased over time reaching adult levels within one year of age [ 18].
Although individual compounds and biochemical pathways were not analysed in detail, it is clear that the usefulness of this new technology in the area of host-pathogen research lies in the opportunity for high-through output screening of metabolic changes, as well as responsiveness of tissues to signals from activated immune cells, for instance, in the context of bacterial infection.
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Three-year follow-up is selected as responsiveness to change of this measurement improves significantly in studies exceeding two years.
These sites for example can influence the general transcriptional as well as cytokine responsiveness of DEFB103 (also known as HBD3), an inducible AMP with important antibacterial and antiviral activity against many pathogens, which threaten epithelia.
Research on the validity of the final version of the Dutch ASCOT as well as the responsiveness of the questionnaire to changes in quality of life as a result of social care service use in the Netherlands is warranted.
Our studies also reveal a key regulatory hotspot on AgrC that controls the basal activity of RHK as well as the responsiveness of the system to ligand inputs.
Our analysis assesses each organizational type's general dialogic capacity as well as the responsiveness of the organizations to requests for information.
If they can do so, Mr. Kwong said Toyota engineers would check tires and the vehicle's suspension as well as the responsiveness of the electronic stability control system, which is meant to stabilize the car.
These observations can be explained by the manipulation of the diffusion and binding of locally secreted cytokines of the IL-6 family, as well as the responsiveness of mESCs to these ligands[36].
Potential interventions could target corporate communication as well as the responsiveness of organizations to employees' values.
However, evidence of in vivo sensitivity of individual AdoMet-dependent methyltransferase reactions as well as the responsiveness of methylation-dependent biological processes to AdoHcy accumulation is limited.
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