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In Canada, an ICER threshold of $100,000 per QALY gained has been suggested as representing "weak evidence for adoption and appropriate utilization" [ 27, 57], although there is no evidence that any Canadian decision-making body has formally implemented this threshold [ 58].
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For the Bayesian analysis, priors were predefined for the mean log odds ratio as a normal distribution with mean zero, and precision 0.001 representing weak prior information.
A peak representing weak acid sites was observed at 250°C.
According to the previous hypothesis in yeast, we expected the difference in scores between conservation-based methods and PWM scan to be bigger on the low peaks as these represent weak binding events.
These could represent weak interactions mediated by inter-membrane surface tension, as implied by immunofluorescence microscopy (see [ 20], and additional files 1 and 2).
In brief, HER2 IHC was scored as 0 when no tumor cells showed positive HER2 membrane staining, 1+ scoring represented weak partial staining of tumor cells, 2+ represented weak to moderate intensity membranous staining of the tumor cells and 3+ staining represented strong circumferential staining of the tumor cells.
Examination of the harvested xenograft tumours showed that the knockdown tumours maintained reduced expression of CKIε, much less robust tumour growth and proliferation rate as represented by weaker Ki67 staining than the control tumours (Supporting Information Fig S6B).
However, the severe degradation of mechanical properties of FRP under high temperature and fire as well as poor sustainability represents major weak points of organic-based systems.
Determining discontinuities is a key step in studying rock mass stability, as they represent potentially weak planes.
This main strategy is implemented as walking along a relatively long rope representing rather weak hereditary prerequisites for weight maintenance.
Similarly, a pair of proteins that belong to the same complex but are not connected due to missing data or an experimental error will be represented as weak siblings.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com