To illustrate how the proposed methodology can be used to overcome resolution limitations, two synthetic examples from the literature [ 33] are used, as they represent particularly challenging cases in module detection.
Accordingly, MiHAs derived from oncoproteins, such as HA-1, represent particularly attractive targets for adoptive immunotherapy of hematopoietic malignancies and solid tumors [49], [50].
Many difficult items suffer rather low discrimination, but because the items cover all the standards, low discrimination items can be interpreted as representing concepts that are particularly difficult for students to master.
It is particularly interesting as representing an architectural move from Burges's favourite Early French style to an English inspiration.
In the last years, particularly since he was appointed foreign minister, Lieberman has positioned himself as representing Israel's "real", "tough" right.
The rash that emerges with telaprevir can be particularly severe, as represented in health state M [ 59, 65].
What's happening this year is we've seen buyers come from areas that weren't as represented in the past, particularly from the Middle East.
The United Arab Emirates (particularly as represented by their capital, Abu Dhabi), Saudi Arabia and Russia are rapidly climbing the ranks of foreign-exchange holders and are hardly holding back in trying to buy up large shares of Western banks (which have suddenly become bargains) and oil companies.
First, there was the French tradition of history and philosophy of science, particularly as represented by Georges Canguilhem, a powerful figure in the French University establishment, whose work in the history and philosophy of biology provided a model for much of what Foucault was later to do in the history of the human sciences.
The design, selection and/or improvement of biomacromolecules such as proteins represents a particularly clear example.
A particularly interesting case is given when the same pathway is affected in both organisms, but through different genes, as this represents a particularly strong argument for the evolutionary conservation of the GATC regulated network, beyond the mere conservation of the sequences themselves.
