However, we are reluctant to disregard the p-value entirely, because as the reference signature database grows and more diverse datasets are included, the p-value may help assign phenotypes to general category (e.g., abiotic stress vs. development).
The verification is done by comparing the mean reference signature " " with a test signature "." The norm is computed and if this norm is less than the threshold for the user, the attempt is accepted; otherwise it is flagged as an imposter attempt [7].
The produced in silico signatures were stored in the reference signature database, through which the expressed MPSS signatures can be mapped on the corresponding EST contigs and singletons based on matches between MPSS signatures and in silico signatures, as described previously [ 38].
The reference signature database therefore consisted of six treatments for the first four time-points, resulting in 24 independent signatures.
The produced in silico signatures stored in the reference signature database, through which the expressed MPSS signatures were mapped on the corresponding EST contigs and singletons based on matches between MPSS signatures and in silico signatures.
Type "re" (as reference), press space.
For the genomic reference signatures, we chose the KEGG organism database (Kanehisa and Goto, 2000) as of March 2010, providing 1013 fully sequenced prokaryotic genomes.
As shown by Table 3, the endmembers extracted by both the OSP-GS and N-FINDR algorithms are very similar, spectrally, to the USGS reference signatures, despite the potential variations (due to posible interferers still remaining after the atmospheric correction process) between the ground signatures and the airbone data.
The fraction of bacterial and archaeal DNA as well as the composition on more specific phylogenetic levels was estimated in the same way by summing up the weights of the corresponding reference signatures.
GeneSign can extract absolute signatures, using as reference populations all cell samples but the ones for which the signature is computed.
