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With respect to quantification of gene products, housekeeping genes have traditionally been used as reference levels for the quantification of nucleic acids (de Kok et al. 2005).
Indicator dummy variables were used to evaluate the distance gradient (reference level > 200 m), the number of roadways near residence (zero as reference level), and the two traffic density approaches (the lowest density levels as reference levels).
In the case of treatment trials for NASH, individual pre-treatment baseline measurements of serum liver enzyme and bilirubin may be optimal as reference levels to assess subsequent acute liver injury.
Furthermore, it will be important to collect normative data from a physically and psychologically healthy sample and another medical sample so as to place the data obtained from cancer patients in a larger population context, and to serve as reference levels.
However, in treatment trials for viral hepatitis the values of liver tests at their nadir, after treatment-induced viral suppression has occurred, may be more suitable as reference levels to assess possible DILI, if liver indicators later rise with continued treatment.
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Taking NaE as reference level, the multinomial logistic regression model was significant (χ 2 = 14.31, P = 0.026).
Selecting the preceding commitment period as reference level (moving base period emissions, mBPE) will level the impact of age-class legacies and extreme natural disturbances to a more tolerable magnitude.
Another measurement was taken, this time using SP as reference level, 3 min after the first one in order to allow correct calibration of the system and bladder detrussor muscle relaxation.
Our ranking uses the mean stability of all considered single-base mismatches as reference level which is independent of the particular triple.
Compared to human dermal fibroblasts in vitro considered as reference level where TRIM29 was barely detected, TRIM29 mRNA was 4.4-fold more abundant in the hepatocarcinoma cell line hepG2.
The low category in each exposure variable was used as reference level.
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