In addition, cases of severe dengue disease can present with atypical clinical manifestations such as massive hemorrhage and organ failure, neurologic disease, myocardiopathy, hepatic and renal failure, and may therefore not be reported as DHF, a problem also recognized in the WHO 2009 guidelines [ 40].
Therefore, for the analysis shown in Figure 1, we assessed additional transitions not currently recognized in the clinical scoring guidelines.
Raters referred to the examples as guidelines at the back of the template in case they could not decide about the type of the level or the indicators they recognized in the transcriptions.
However, in these data, we found widespread use of urine testing in the absence of signs and symptoms recognized in clinical guidelines as indicating the presence of a UTI.
Neuron specific enolase has been recognized in recent guidelines developed by the American Academy of Neurology as a useful prognostic indicator in comatose patients with global hypoxic-ischemic brain injury [ 6].
This is only one of many reasons why the need for sufficient patient monitoring as an element of safety is recognized in current guidelines [ 4, 15].
Because of its efficacy and tolerability profile, MPH is recognized in treatment guidelines in Europe and the USA [ 8- 11].
This is recognized in guidelines for reporting observational studies, including the US FDA guideline, 'Best Practices for Conducting and Reporting Pharmacoepidemiologic Studies using Electronic Health Care Data' [ 1].
(Market Efficiency Rpt. 12; Damages Rpt. 30). As a foundation for the identification of significant or "material" information, Dr. Hakala and his staff applied the categories of material information contained in the NASD guidelines, as recognized by the Securities and Exchange Commission, together with third party news and analyst reports recognized as material in the academic literature.
The importance of documenting this is widely recognized in guidelines for reporting diagnostic accuracy studies such as STARD [ 22].
The need to address ethical issues in global health training has also been recognized in proposed ethics guidelines [ 30- 33].
