Accordingly, p130Cas silenced cells reorganized in colonies that lost their elongated protrusions, acquiring a more polygonal shape, as quantified by a marked decreased in length/width ratio.
DNA-bound platinum, as quantified by ICP-MS, showed a significant reduction in metformin treated cells by 19.3% in WHCO1, 14.1% in WHCO5 and 18.4% in SNO cells.
Based on LR Chi2 (2) = 12.62, the model was significant as quantified by a p-value = 0.0018.
Although some significant results were achieved when investigating the association structure between CAFs (Supplementary Table 1), no strong correlations (as quantified by a coefficient ρ>0.80) were detected.
This was accordingly quantified as a significant decrease in the CD44 raft affiliation ratio.
Gel cell matrices degraded in approximately 3 weeks, as shown by a significant decrease in dry gel mass.
Testosterone inhibited both bone formation (as evidenced by a significant decrease in double-labeled surface and serum osteocalcin level) and bone resorption (as evidenced by a significant decrease in RANKL mRNA expression), so bone remodeling was halted.
The overall content of fatty acids, as quantified by GC-FID, decreased in mutants significantly compared with wild type for all the strains except the fat-7 mutant.
In addition, the decrease in colony-forming ability was accompanied by a significant decrease in colony size as compared with the control.
Tolerance manifested as a decrease in seizure threshold to near-control values, while withdrawal hyperexcitability was evidenced by a significant decrease in seizure threshold below the control value.
