The phrase "as primary origin" is not correct and may lead to confusion in written English.
It could be used in contexts discussing sources or beginnings, but it lacks clarity and precision.
Example: "The study identifies the as primary origin of the phenomenon as a significant factor in its development."
Alternatives: "as the main source" or "as the principal origin."
Conversely, B2 clone CC32 was significantly associated with a non urinary tract origin as primary source of infection (p = 0.023).
Indeed, miR profiles allowed us to classify human cancer of unknown primary origin as well as poorly differentiated tumors [ 25, 26].
This is supported by a report demonstrating the ability of miRNA profiles to correctly classify human cancers of unknown primary origin as well as poorly differentiated tumors [ 16].
Pediatric tricuspid regurgitation is likely to be related to annular dilation of primary origin, as it occurs without heart failure or elevated pulmonary artery pressures.
In contrast, the higher rates observed in the H1N1, H3N8 and H4N6 subtypes could be due to their primary origin as infections of wild birds with multiple low pathogenicity strains in the large avian reservoir.
Co-localization of a-EpCAM1 and ER-TR7-staining in the aging thymic medulla (Figure 1D) confirms that in the 9 month old thymus there are cells expressing the EpCAM1 marker as a legacy of their primary origin, and also secreting ER-TR7-positive extracellular matrix components, a function conventionally attributed to fibroblast cells.
However, since organs may consist of two or more types of cells, using the primary origin site as classification criteria may not provide the most accurate and precise definition of tumors.
In primary and metastatic lung cancer and liver metastasis from different primary origins, as much as 10 30% of the tumors are reported to use this alternative blood supply.
Cancer of unknown primary origin presents a clinical challenge as the origin of tumour tissue is crucial for selecting proper treatment plan.
