Data from the field studies revealed that when releasing a fixed population, there are diminishing returns on the probability of recapture as higher numbers of marked mosquitoes are removed from the pool of potential responders.
As the current treatment paradigm largely uses anti-TNF therapy after the failure of oral disease-modifying antirheumatic drug (DMARDs), we selected the classifier to minimize the false identification of non-responders (i.e., the incorrect identification of responders as potential non-responders) and maximize the specificity of the classifier.
Regarding the special case patient who received three doses of DIMS0150, the biomarker assay confirmed that the patient was steroid refractory at time of first dosing and classified as a potential responder to DIMS0150.
Therefore, internal organs (spleen, head kidney and liver) were also chosen as potential tissue responders to delayed infection-by-immersion and to compare their responses with those obtained at the fin bases.
The NE pattern in castration-resistant prostate cancer (CRPC) may prove useful in selecting potential responders to target therapies such as somatostatin analogues.
Potential responders within the patient cohort.
Their method could be used as a diagnostic tool to determine potential for recruitment in individual patients, who could then be stratified as possible responders or nonresponders in a clinical study of a recruitment strategy that applies only to responders.
In the Lincolnshire pilot, a fire ambulance – or 'fambulance' as control room operators have dubbed them – is only dispatched if it is the nearest potential responder to a red one or red two emergency – the most serious.
All this does is make the potential responder feel like they just got a homework assignment.
First, the use of an online panel provider has precluded description of non-responders and potential responder bias.
Several ongoing R&D and fielded communications solutions are described as potential solutions for the first responders.
