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Nevertheless, as pointed out in the text, the tree presented here is consistent with all previously established relationships between DHH protein families.
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However, as we pointed out in the text, in the type I-C systems, the Cas5 family probably substitutes for the Cas6 function using a potential catalytic histidine in a different location.
As pointed out in Sect.
However, as pointed out in Sect.
This is now pointed out in the text.
As pointed out above in the response to Reviewer 1, three supplementary tables have been merged into the main Tables 1 and 2, and one supplementary Figure (now Figure 6) has been moved to the main text.
Authors' response: Yes, this is pointed out in the revised text.
We have mainly modified text in the "Corpus selection, annotation and properties" section to simplify the ambiguous texts, as pointed out by Robert Leaman.
However, as pointed out by referee two, we present both hypotheses and said carefully in the text that our phylogenetic analysis as the domain organisation of Topo IB homologues "strongly suggest".
As pointed out by Taavitsainen (2001: 141), we assume that genres or text types involve particular codifications of linguistic features and, in consequence, the choice of a given genre or text type affects the set of grammatical choices.
Update: As some of you have pointed out in the comments, BranchOut recently changed the text on its invite button from "Connect" to "Share" a move that could have contributed to the 2400% growth in January.
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