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As the second scheme local error estimators are presented.
The second scheme, denoted as simple-SR, is for ME with a simple BW adaption scheme.
But 41% chose the second scheme.
The second scheme, the random allocation rule, selects at random any assignment of the given number of subjects per treatment.
We have used here the second scheme.
But three years in, the first scheme was widely seen as being tired and uninspiring.
The differential taxon sampling applied in the first scheme (balanced) was performed as follows.
In the first scheme, patients initiated therapy using label-indicated starting doses of simvastatin – a commonly prescribed generic statin, but not the most powerful generic option – as defined by LDL-C reduction per milligram dose.
The first scheme, denoted as fixed-SR, is for ME without any BW adaption scheme.
The first scheme is a centralized scheme.
It's also the first scheme of its kind.
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