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The data presented herein was provided with all clinical identifiers removed as per HIPAA guidelines.

The efficiency of bioconjugation was determined as the degree of labeling per tetramer (the measured absorbance data presented as Table S2 in Supporting Information).

The retinal vessel vascular area was measured in five random areas of five sections per eye and data presented as retinal vessel area in µm per µm.

The authors declare that the data and materials presented in this manuscript can be made publicly available by Springer Open as per the editorial policy.

Authors declare that the data and materials presented in this manuscript can be made publically available by Springer Open as per the editorial policy.

I declare that the data and materials presented in this manuscript can be made publically available by Springer Open as per the editorial policy.

Mean energy expenditure data presented as metabolic equivalent thresholds per hour per day.

Data presented as percentage change per year.

a. Data presented as DDD/1000 inhabitants per day b.

Data presented as mean plus SEM for 20 wells per condition.

Data are presented in mg/kg per day as mean ± standard deviation.