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High-volume hemofiltration (HVHF) was used as rescue therapy in patients evolving with refractory septic shock.
As the population of patients evolves over time and patients with milder disease are treated, it is highly likely that any cost effectiveness analysis would suggest that a minor benefit potentially conferred by plasma exchange would come at too great a cost when compared with IV methylprednisolone.
All patients evolved favorably.
Seventeen per cent (n = 6) of patients initially classified as Knaus A before ICU admission evolved to Knaus B (the same number was observed for Knaus B patients evolving to Knaus C) and 5% (n = 2) of Knaus A patients evolved to Knaus C.
Two patients evolved from solitary plasmacytomas.
Twenty-eight (46%) patients evolved to death.
Sub-clinical inflammation of the gut is present in up to 60% of AS patients, and this inflammation can evolve into fullblown inflammatory bowel disease [ 79].
We observed a better outcome (higher number of well-preserved maculas and fewer atrophic eyes) in eyes that started treatment after 2010, but the number of eyes in this group was low and the shorter follow-up period may explain this result, as patients are less evolved.
Treatment strategies for these patients will evolve as new drugs are continually being developed.
Its successful initial use in rheumatoid patients has evolved, as has its design, to allow use in osteoarthritic patients and patients with posttraumatic arthritis.
Haematological oncology is changing rapidly, with new approaches to treatment and diagnosis continually emerging as diverse patient pathways evolve.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com