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However, single high dose administration of 300 mg artesunate as one dose, followed by mefloquine on day 24 and 30 h, resulted in a 97% cure rate of malaria patients in Thailand [ 19], which indicates that short treatment regimens of artemisinin-derivatives with appropriate combinations are effective.
The patient received parenteral antibiotic treatment, with 1.5 g of cefuroxime per 8 h, during his hospitalization, as well as one dose at the emergency department and one while on the operating table.
Frankenweenie was viewed by some as one dose too many of Tim Burton's goth whimsy with a copout ending.
The RD was defined as one dose level below the MTD.
The recommended dose was defined as one dose level below the MTD.
The MTD was defined as one dose level below which ⩾2/6 patients experienced a DLT.
Similar(40)
Experiments were performed with cells cultured under control conditions as well as submitted to one dose of radiation combined with 5-FU treatment (see details in Methods).
For the twice weekly schedule, completion of Cycle 1 was defined as receiving one dose of trastuzumab and at least three doses of retaspimycin HCl.
For primary human hepatocytes, the Wilcoxon test was used as only one dose of LPS was explored, due to the limited availability of primary human hepatocytes.
In phase 1, changes in lipids and lipoproteins were not statistically compared between the seven treatment groups, as only one dose of FM-VP4 was administered.
However, as only one dose of antibody was used, it is difficult to evaluate from this unpublished study whether targeting TGFβ ligand may be an appropriate anti-fibrotic strategy in SSc.
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