The phrase "as minimal changes" is correct and usable in written English.
It can be used when discussing adjustments or modifications that are slight or not extensive.
Example: "The project was completed with as minimal changes as possible to maintain the original design."
Alternatives: "with minimal alterations" or "with slight modifications".
Smaller values of (rho ) may lead to a lengthier training as minimal change is obtained during strengthening while large values may drive the network towards instability.
Diseases of the podocyte most commonly manifest as minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) in children and adults, respectively.
Two patients in the idiopathic category presented with nephrotic syndrome and were diagnosed on light microscopy and immunofluorescence as minimal change disease.
The signs of renal dysfunction may be caused by lupusunrelated renal injury such as drug toxicity or infection or by lupus-associated mechanisms that are not part of the classification, such as minimal change nephrotic syndrome or thrombotic microangiopathy.
There have been a number of small studies recently that have shown promise in accurately diagnosing specific diseases such as minimal change disease, IgA nephropathy and pre-eclampsia by identifying disease-specific urinary proteins [ 24– 31].
Moreover, high SuPAR serum concentrations were found in patients with primary FSGS, but not in those affected by other glomerulopathies, such as minimal change disease (MCD), membranous nephropathy, and preeclampsia [ 27].
Childhood nephrotic syndrome with bland urinary sediment is usually managed as minimal change disease and renal biopsy is not necessary for the diagnosis unless there are unusual features [ 1].
Unfortunately not all glomerular diseases have routinely available biomarkers, in particular those more common conditions such as minimal change disease, presenting a diagnostic and management dilemma in the pregnant nephrotic patient.
