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Exact(3)
While a log-rank test can determine the risk of death systematically, i.e. if it is higher or lower in one group over a whole period, another approach, as mentioned in the study by Kunikowska, has been to apply a proportional hazards or Cox regression model.
Total DNA from the parents of different mapping populations and F2 lines derived from ICP 28 × ICPW 94 were isolated from two to three young leaves following the standard DNA isolation protocol as mentioned in the study of Cuc et al. The DNA quantity for each sample was assessed on 0.8% agarose gel.
As mentioned in the study, a Kappa coefficient was used to determine the reliability of this scale and the results indicated that the scale is reliable if it is used by practitioners who are familiar and have good knowledge of their clients, however, the study did not provide a measure for the reliability coefficient.
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Moreover, as mentioned in the studies, the technique and condition of performance were of wide variability.
As mentioned in the studies of Kulis et al. [ 22] and Ferreira et al. [ 24], gene expression data 'as is' is not sufficient to cluster patients into the two classes (see also Additional file 3: Figure S9).
As mentioned in the previous study [ 12], the rest non-miRNA reads could be other small non-protein-coding RNAs or degradation product of mRNA.
As mentioned in the earlier study [ 21], it is not clear whether the patterns and sequence of events observed with the current selection of patients can be generalized to patients with a slower or faster disease progression rate.
This study demonstrated the expected effects of each drug as mentioned in the previous studies.
Naturally, these scenarios have a strong influence on the tools that were developed or applied to each context, as mentioned in the selected studies.
As mentioned in the introduction, studies evaluating the relationship between duration of diabetes and periodontitis have inconsistent results [ 16- 19].
The role of resistin in insulin resistance and various chronic diseases is well established as mentioned in the above studies [ 4, 51].
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