We observed no significant difference in aortic root diameter between wild-type and βarr2−/− mice at 8 wk of age, as measured by repeated-measures, two-way ANOVA with post hoc Bonferroni testing (Fig. 2 F ). Multiple proaneurysmal genes and proteins, such as MMP-2 and -9, are upregulated in aneurysmal aortic tissue in murine MFS models (8, 36, 37), as well as human MFS patient samples (32).
Vinson et al showed that a fifty minute lecture for first and second year medical students could have immediate effects on knowledge as measured by repeat anonymous survey six weeks later [ 15].
Prior to commencement of the Year 4 in-school week, we found no significant difference between the two groups in relation to retention of knowledge or reasoning, as measured by repeat administration of the same multiple choice and script concordance tests.
The activities were measured by repeating three times.
All the new mutations (R631Q, R671W, V867M, H925Q, R951W and G1063S) have not been identified previously and demonstrate reduced in vitro telomerase activity as measured by the telomere repeat amplication protocol (TRAP) assay (Figure S1).
Since a previous study has reported an inverse association of maternal 25(OH D in pregnancy with offspring insulin resistance as measured by HOMA-IR, 8 we also repeated analyses with this measure as an outcome, calculated using the standard formula.
In addition, tolerance to the compound did not develop after repeated daily dosing, as measured by hypothermic induction as well as attenuation of d-amphetamine induced hyperlocomotion.
Lifetime psychotic symptoms in high-risk offspring with a remitted mood disorder significantly influenced the stability of cortisol daily secretion over repeated sampling years as measured by AUC.
Molecular masses of PrPres glycoforms were determined as the average of the center positions of the bands from at least 3 repeated electrophoretic procedures, as measured by comparison with a biotinylated marker (B2787, Sigma, Saint Louis, MO, USA) included on each gel.
