The number of embryos in the brood pouch and adult mortality serve as main endpoints.
As far as the main endpoint was considered (percent time with intragastric pH > 3), there was no statistically significant difference between both drugs.
The use of inpatient death as the main endpoint (vs. mortality within a fixed time, such as 30 days or one-year from admission, data not available in our study) involves several inconveniences [ 48].
2 Although we did not study specific complications, we focused on reintervention as a main endpoint of our analyses.
We chose the body mass index (BMI) as the main endpoint because its components can be easily measured and it can be easily compared with published data.
These publications focused on revision surgery as the main endpoint and did not present any specific information about patients without symptoms of implant failure.
Of note is that most studies have evaluated plasma drug levels as the main endpoint and only a few evaluated lung tissue levels.
As the main endpoint was the percentage of patients with an Hb level within 10 12 g/dl (as per 2007 EMA guidelines) around 6 months of C.E.R.A. treatment, the sample size determination was based on estimation of a proportion.
In this analysis, we use the serum HBV DNA level as the main endpoint for the various rescue strategies and for estimation of the risk of cirrhosis and hepatocellular carcinoma.
The RR, HR or OR with the greatest degree of control for other environmental and dietary risk factors, and their corresponding 95% CIs for incident prostate cancer risk were extracted as the main endpoint.
The prevalence of multimorbidity has been estimated at more than 80% among persons aged older than 85 years. 2 Up until now, clinical research has focused predominantly on single disease and episode, often with a focus on mortality as the main endpoint.
