The depletion of target sites within the first 20 nucleotides immediately downstream of the stop codon suggests however that the very beginning of the 3'UTR region is a suboptimal area for targeting, as it may be obstructed by the ribosome complex.
Nonetheless, long-term stent patency is a limiting factor with uSEMS as well, as these devices may obstruct due to epithelial hyperplasia and tissue ingrowth through the stent meshes [ 15- 17].
However, there exist, in addition, local disabling factors such as erratic power supply, low level of penetration, low level of Internet literacy as well as cultural factors which may obstruct the significance of the Internet for reproductive health information among the girls in the city.
As pancreatic cancer may obstruct pancreatic enzyme flow, pancreatitis may be a consequence of pancreatic cancer.
If a baby fails to rotate, another part of its body, such as its shoulders, hands, or feet, may obstruct the birth canal, which is painful and dangerous for the mother and infant.
It may be even worse (e.g. Kendell and Jablensky 2003 and references therein): the DSM classification may obstruct scientific progress, because it forces to compare heterogeneous cohorts ('apples and pears') for common characteristics ('genes, colour', etc).
Obstacles such as severe soft tissue damage or hyphema may obstruct the visual access to the pupil, thus rendering direct PLR observation difficult or impossible.
Instead, it appears that interruption of normal clock rhythm may obstruct cancer growth.
Not as much as it may seem.
