The phrase "as it is significant" is correct and usable in written English.
You can use it when you want to emphasize the importance or relevance of something in a particular context.
Example: "The research findings are crucial, as it is significant for future studies in this field."
Alternatives: "because it is important" or "since it holds significance".
It was an unusual move, "as surprising as it is significant," wrote the political commentator Mark Halperin.
Perhaps that's because, like my mother's influence on my own cooking, much of Delia's impact on all our dinner plates and shopping baskets is as unnoticed as it is significant.
"In two years, we have performed a structural recovery," the president said on Tuesday, that "is as unprecedented as it is significant".
It is important to understand and predict the behavior as it is significant in the remediation of hydrocarbon polluted sites (Hunter 1981; Bruell et al. 1992, Wise 2000) and in oil recovery (Amba et al. 1964; Haroun and Chilingar 2009; Al Shalabi et al. 2012a; Chillingar and Haroun 2014) in reservoirs.
What we found was as surprising as it is significant.
§Included term for proportion of rotavirus tests positive in the model, as it is significant and positive (p<0.05).
Trial status was included in the model as it was significant in univariate analysis.
That is, the smallest PRESS was selected as long as it was significant at a predefined level (e.g., p = 0.01); otherwise, the second smallest PRESS was examined.
We included the complexity covariate (defined as "primary" or "complex primary" in the database) as an adjustment factor in our analyses of mortality as it was significant.
The association between nasal S. aureus carriage in infants and mastitis in their mothers (adjusted OR 3.19, 1.23, 8.29) appears to be robust as it was significant in each logistic regression model.
Also as was already explained, interaction between baseline value and visit, allowing for time varying effect of baseline severity, was included in the model as it was significant in most of the cases.
