Given a weighted human interactome represented as a matrix W corresponding to the interaction strength between genes, and a set D of k known disease-active genes as seeds, we define vector x = (x1, x2,..., x n)T as initially known activity of genes in the disease, with x i = 1 if gene i is in the set D, x i = 0 otherwise.
The plan was to sell Crazy Otto, as it was initially known, as a kit to arcade owners, which they could use to modify their forsaken Pac-Man cabinets.
Many of the 19th-century English companies that made "block chocolate", as it was initially known, were owned by Quakers: the Frys, the Cadbury brothers, the Rowntrees, the Terrys.
For example, Hurricane Karen in 2001 was initially known as Subtropical Storm One as well as AL1301 (or 13L for short).
It is the only PI co-formulated as a fixed combination of lopinavir (LPV, initially known as ABT-378) and ritonavir (RTV).
The story opens and closes with a voice-over belonging to a man you come to know as Pedro da Silva, but initially know as a 14-year-old called "just João" (played as a teenager by João Luis Arrais and as an adult by Afonso Pimentel).
Initially known as Google Advise there, it started out as a tool to sell car insurance launched last March before the company added mortgages to the stack in November.
A photo-reconnaissance version of the Savage, initially known as the AJ-1P, but later designated as the AJ-2P, was ordered on 18 August 1950.
Kepler-4b, initially known as KOI 7.01, is an extrasolar planet first detected as a transit by the Kepler spacecraft.
As it was claimed to have been spread by French troops, it was initially known as the "French disease" by the people of Naples.
That aid effort, initially known as Concern Africa, shortened its name to Concern in 1970 as it broadened its efforts, seeking to provide food, medical support and education in many of the world's poorest countries.
