The phrase "as initially discovered" is correct and usable in written English.
It can be used to refer to something that was found or identified at the beginning of a process or investigation.
Example: "The results of the experiment were consistent with the findings as initially discovered in the preliminary study."
Alternatives: "as first found" or "as originally identified".
Fas (also known as CD95) was initially discovered as a cell surface molecule that efficiently triggers death signals when bound to its ligand, Fas ligand (FasL) [ 7, 8].
SOCS3, as its name suggests, was initially discovered as a molecule that interferes with cytokine signaling.
As mentioned earlier, LAMR was initially discovered as a cell surface receptor for laminin.
As mentioned previously, Brc1 was initially discovered as an allele-specific, high-copy suppressor of smc6-74 (Vetkale et al. 1999).
As a member of ubiquitin-specific protease family, USP33 was initially discovered as a substrate protein binding to VHL E3 ligase (Li et al., 2002).
ARC was initially discovered as an endogenous apoptosis inhibitor in postmitotic cells, such as cardiomyocytes, skeletal muscle cells and neurons.
More recently, CTX-M-type β-lactamases, a small but growing family of broad-spectrum class A β-lactamases, were initially discovered as MEN-1 (EMBL accession no. X92506) and also later found as Toho-1 in Japan in 1993 (4 ).
The substance was initially discovered as a component of endogenous monoamine oxidase (MAO) inhibitory activity, tribulin, and subsequently identified as a selective inhibitor of MAO B [12].
Mouse Tregs were initially discovered as CD4+CD25+ cells by Shimon Sakaguchi in 1995, and their human counterparts were firstly characterized as CD4+CD25+ T cells in 2001.
Initially discovered as a growth factor antagonist with involvement in developmental processes, Sprouty is now recognized as a versatile modulator of ERK that also impacts other pathways to control crucial physiological processes in interaction with an increasing number of effectors, mediators, and regulators.
