Sentence examples for as initial signal from inspiring English sources

TLRs have been implicated as initial signal transmitters under such clinical conditions [ 2, 4, 37].

The DDR response can be envisioned as a signal transduction cascade in which DNA lesions act as initial signals that are detected by sensors and passed through transducers [11], [12].

ARGOS and ARL are targeted to the endoplasmic reticulum, the same subcellular location as initial signaling elements in the ethylene pathway.

For substorm onsets, earthward flowing ions appear as an initial signal of the onset in the near-Earth plasma sheet in the onset sector.

An increased metabolic load (metabolic demand per cell or M/N) induced by partial hepatectomy serves as the initial signal inducing regeneration in the model (Additional file 1: Figure S1).

As the initial signal fades, reduction of GM3 and GD3 could contribute to a second 'burst' of IL-6 expression by alleviating the suppressive effects of these gangliosides on IL-6 itself or on TLR4.

Results in Figure  6 show that NOX4 protein expression and ROS production are clearly affected by both pharmacological inhibition and knocking down of JNK, putting this signaling pathway, and not the canonical Smad2/3 route, as the initial signal of a sequential mechanism that ends in tumor fibrosis.

Interestingly, the ethylene receptors as well as the initial signaling elements in the pathway are predominantly localized to the endoplasmic reticulum (ER) [ 4].

This is of particular importance in Fas/CD95-mediated signal transduction as the initial signaling events depend on protein-protein interactions [1], [4], [8].

However, electrical synapse is passive, which means that the signal received in the receiver side is the same as or smaller than the initial signal from the sender side, called 'lack of gain'.

The kinetic experiment started by switching on the light source after the spectral signal of the Orange II in the suspension reached a steady state; this actual initial signal was taken as a measure of the initial concentration of the dye.