In paediatric severe Dengue infection, hypertonic sodium lactate induced a partial recovery from endothelial dysfunction, as indicated by a significant decrease in sVCAM-1 [31].
The FD protocol was effective as indicated by a significant reduction in urine output.
Renal dysfunction as indicated by a low eGFR was classified as mild 60-899 ml/moderate m), moderate (30-59 ml/min/1.73 m), and severe impairment (15-29 ml/min/1.73 m) [ 35].
The injury induced severe pulmonary dysfunction as indicated by a progressive decline in oxygenation index and concomitant increase in pulmonary shunt fraction.
Reduced afterload may have facilitated ventricular ejection as indicated by a small increase in ESWth and thus masked a systolic dysfunction, but no change in the load independent variable PRSW indicated preserved pump function.
This rapid growth is being fuelled by significant investment in research and development and breakthroughs in sustainable technologies, as indicated by a spike in patent applications.
Differences were considered statistically significant when p<0.05 (as indicated by an asterisk on the figures; n.s., not significant).
A p < 0.05 was considered statistically significant, as indicated by an asterisk in the table.
Instead, these data suggest that a decrease, in proteasome activity with aging contributes to cellular dysfunction in skeletal muscle, as indicated by an increase in ER stress.
However, there was significant heterogeneity of this effect as indicated by an I2 statistic of 89.5%.
Furthermore, oxidative stress, as indicated by methemoglobinemia in our patients, is discussed as an aggravating factor for endothelial dysfunction and cell damage [ 5, 6].
