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Although it was unclear whether these beneficial effects were temporary in nature, many studies showed positive outcomes, and the meta-analysis indicated a reduction in the mortality as well as in the recurrence of myocardial infarction.
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Accordingly, it will be critical for future work to consider the relative contribution of developmental changes in neurobiology (e.g., altered neurotransmitter activity and connectivity, onset of pubertal hormones), as well as the recurrence of disorder in accounting for the progressive HPA axis dysregulation associated with depression across the lifespan.
The associations between expression of the gene group scores (as calculated in the Recurrence Score) and risk of breast cancer death were generally stronger than those for individual genes.
Here, effective tertiary prevention is defined as a reduction in the recurrence rate for people with highly recurrent (≥ 3 episodes) disorders to the same recurrence rate as those who have had only one past episode.
ER and PR were found to be positive in the recurrence as well.
Notably, mutations in these genes have been previously identified as potential driving events in the recurrence of other doxycycline-driven transgenic mouse tumour models [ 15, 16].
With our MKL analysis, one of the highest significance pathways is RNA transport, which has been previously reported as a key pathway in the recurrence of non small-cell lunon small-cellet alung2012).
The determinism is related to the predictability of the system (as the length of diagonal lines in the recurrence plot indicates how long neighbouring points remain close) and to Lyapunov exponents (time constants of exponential divergence of close trajectories of a chaotic system [ 31]).
This difference was mainly attributable to stage II patients, as in this group the recurrence rate was 13.2% for patients with MSI tumors and 27.9% in MSS cases (P = .06).06
In the present study, we examined the association between preoperative serum levels of lipocalin-2 and MMP-9 and disease-free survival (DFS) and determined the potential of both proteins as noninvasive biomarkers in predicting the recurrence of breast cancer.
Autism has a strong genetic component, as indicated by the recurrence risk in families and in twin studies [ 28].
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