Currently known distinct expression profiles of CD19 by human plasma cell subsets, experiences with anti-CD19 therapies in malignant conditions as well as the rationale of targeting autoreactive plasma cells in patients with SLE are discussed in this review.
This paper will discuss the design of an online learning environment for foreign correspondents, the resources and translation required to maximise the success of asynchronous online discussion groups, as well as the rationale of delivering complex content in a foreign language.
Such analysis would yield insight into the molecular mechanisms of DXR injury in oocytes and other tissues as well, and would help in the rationale of designing more effective treatment strategies to circumvent the unwanted side effects of this drug.
This work eventually appeared in English as The Rationale of Reward (1825) and The Rationale of Punishment (1830).
The conceptual construct used in this study considers a BM as "the rationale of how an organisation creates, delivers and captures value" or, in other words, as "the organisation's core logic for creating value" (Linder & Cantrell, 2000: 12000
Even though they discuss priority setting of health interventions, and not health research as focused here, the rationale of aggregating criteria in subsets was useful to reduce the original list of criteria used in our study, and helped define the final list of criteria submitted to respondents.
As the rationale of including the control strains in the assay is to take into account the possible non-specific effects (e.g., toxicity) of the sample on bacterial bioluminescence, the high initial bioluminescence allowing more accurate measurement of the inhibition of bioluminescence, is certainly a bonus.
In this paper the rationale of the Polish MOBIT project as well as its design is presented.
The rationale of using AS in chemical burns derives from the fact that it contains antiproteases such as alpha 2 macroglobulin (which reduces collagenase) and vitamin A (which modulates the normal growth and differentiation of the epithelium) [ 38, 67].
As stated in the introduction, it realizes the rationale of minimizing the impact of out-of-date data (e.g., CPU load measurements, filters' selectivity estimates) on the analysis and reoptimization phases of an AQP technique, while triggering re-optimization only when a meaningful change occurs.
