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In figure 3 D, we show a scenario of the formation of strata 4 and 5 consistent with the isochromatid model, but in any case, our results clearly point toward a single inversion event spanning the whole stratum 5 and another similar event for stratum 4.
According to the isochromatid model, two pairs of staggered single-strand breaks yield long 5′ overhangs, which are filled-in by DNA synthesis.
We tend to favor the latter because it is more parsimonious (one event the inversion in the isochromatid model with staggered single-strand breaks instead of two events—a duplication and an inversion in the nonallelic recombination model).
The Y inversion itself could have produced the duplicates as in the isochromatid model.
More recently, a multigenome comparison in Drosophila revealed that 60% of the inversions produced duplications and were formed by a mechanism called isochromatid model with staggered single-strand breaks (Ranz et al. 2007).
This magazine wasn't as tasteful or as artistic as Playgirl in the models were photographed.
For the works titled YIN, for example, Hack had to paint the model in the round, as she moved the model in front of the background.
"Our business model in Canada is not the same as in the US because the legal model is not the same".
Anyone that is dealing with cancer understands there are gaps in the medical model as there are with any model.
The resulting model used around 15,000 pieces, 1,000 of which are just used as scaffolding for the base and can't even be seen in the final model.
In the morning, the car was as dead as a Model T in a blizzard.
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