However, as important drawbacks are the fact that only renders mean telomere length values per sample and does not allow the quantification of short telomeres.
Consequently, the failure of liberal dispositionalism to advance the physicalist thesis might be seen as an important drawback.
As an important drawback, mobile devices present security concerns related to how the operating system controls the way that installed applications access memory data and communication buffers.
Computer Vision is one of the most intensive data processing fields, and conventional systems do not provide any mechanism to address adequately this task, so this issue comes up as an important drawback.
As an important drawback of SAGE is that a large amount of messenger RNA (2.5 5 μg polyA RNA) is required, and our tissue supply was limited (a punch biopsy) we employed the MicroSAGE protocol in RNA thereof [ 21].
As discussed, an important drawback in classical screening methods is that large molecular databases (usually containing millions of compounds) have to be screened to find potential drug candidates.
It was surprising because acetabular erosion is mentioned as the most important drawback of HA.
This is an important drawback as validity evidence supporting the use of this scale among apparently healthy adults (e.g., [ 5, 11, 22– 25]) may not generalize to cancer survivors as measurement properties may differ across populations [ 26, 27].
Furthermore, the inability to perform a bypass graft and the significant endoscopic skills required can be considered as other important drawbacks, making the ventral corridor indicated only in very selected cases.
Accordingly, the prediction accuracy for H3 loops is not equally satisfactory as for the other loops, an important drawback because the H3 loop is central in the binding site and therefore often essential in determining the antibody antigen interactions.
