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This suggests the interpretation of other FRPs' experiences has a conditional effect on the diffusion process and its mechanisms, as illustrated by changes in the relative effectiveness and payoffs associated with a new master frame [11, 75].
Abot et al. (2013) were able to use tamoxifen (an AF1-dependent estrogenic ligand) and mutations that disabled AF1 activity of the ERα to demonstrate roles of AF1 as illustrated by changes in transcription or biological end points.
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On the one hand, loss of a TFos can increase fitness, as dramatically illustrated by changes in the regulation of pitx1 in three-spined stickleback that lead to advantageous anatomical changes in a new environment.
Equally important, it helps us understand the mechanisms that influence the evolution of the IF, as illustrated by the changes in the impact factor of Cell and New England Journal of Medicine (NEJM).
While infection intensity declined significantly in the oldest age group, anti-Sh13 IgG3 levels remained high so that the relationship between levels of this response and infection intensity is uncoupled as illustrated by the changes in the correlation between infection intensity and levels of the antibody in this age group.
Importantly, the transcriptional modulation observed was very consistent over the time period as illustrated by the fold change of these selected genes (Additional file 1: Table S1).
Our study revealed a consistent increase in complexity during the evolution of vertebrate mammals from the perspective of protein families as illustrated by the positive change in the protein family and domain indices at the corresponding lineages.
Also, we showed that cellular mechanisms involved in MP toxicity can be consistently detected, as illustrated by the gene expression changes listed in Table 4.
As illustrated by the need to change categorical values into numeric values, it is important at design time to take into account the type of research questions that will need to be answered.
The overall analysis of transcriptome profiles (as illustrated by heat maps; fold-change >1.5; P < 0.05) revealed a characteristic molecular pattern for each group, but with many more similarities between zidovudine and tenofovir samples than between zidovudine or tenofovir and control samples (Fig. 2a).
Most of the variants seemed to have evolved from their antecedent temporal variants with a varying number of nucleotide changes, as illustrated by comparing variant 2004 to variant 2002.
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