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Augmented oxidoreductase gene expression suggests that oxidative stress may contribute to respiratory muscle dysfunction, as has been implicated with diabetes in other tissues [61].
The timing of PNN proliferation within the matrix introduces the possibility that these proteoglycan structures may be involved in a similar maturation process for the neostriatum as has been implicated in the cortex and other brain areas [46], [47], [55], [59], [91] [93].
The modular architectures of MaSp1 and MaSp2 likely reflect concerted evolution within a single gene, as has been implicated in maintaining similarity among Flag (∼440 aa) ensemble repeats and the long repeats of TuSp1 (∼200 aa) and AcSp1 (aciniform silk; 200 aa [14]).
Importantly, AS has been implicated in plant immune responses more directly through the identification of R-gene splice variants for a great number of resistant proteins [ 60].
Nevertheless, the involvement of PKA in Hh signaling does allow the pathway activity to be regulated by other GPCRs, as has been implicated by several recent studies.
The supported bilayer system used in the TIRFM experiments precludes curvature and bridging, and the small sonicated vesicles used for stopped-flow likely prevent the induction of negative curvature, as has been implicated for Syt1.
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In 1999, WNV was identified in North America (2 ) and has become the leading cause of arboviral encephalitis in humans and horses (3 ), as well as having been implicated in deaths of members of at least 198 bird species (4 ).
Our results suggest that the most likely source of this outbreak was the same dairy goat farm, Farm A, as had been implicated in a smaller outbreak in the area the previous year.
As IRF1 has been implicated as an inducer of apoptosis, we decided to explore the role of IRF1 in the context of BV6-triggered apoptosis in more detail.
A type of platelet-derived vesicle, known as exosomes, has been implicated as a mediator of apoptosis in patients with sepsis [ 13].
Rapid reduction of immunosuppressive therapy such as steroids has been implicated as a predisposing factor for the development of PCP in HIV-negative patients [ 11, 17, 23, 24].
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