As general features, physicochemical properties and cell performance degradation/failure are correlated and bridged by the electrode reaction mechanisms.
Global reduction in DNA methylation and global alterations in histone PTMs have been identified as general features of neoplasia [12], [13], [14], [15], [16].
Excluding COGs R and S (categorized as General features and Hypothetical Functions, respectively), the data indicate that the majority of the unique genes belong to COG K. COG K refers to transcription and the majority of these unique genes are transcriptional regulators.
As general features, proteins classified as IDPs possess low-complexity regions, low hydrophobic amino acid content, and therefore highly polar characteristics and charged amino acids [ 34, 35].
ColoWeb has stored several features from separate cell lines to allow users to make cell-line specific comparisons, as well as general features common to all cell lines.
In this review, we focus on the initiation step of DNA replication, especially loading of replicative DNA helicase onto origins and discuss its diversity as well as general features in various organisms.
The role of epigenetics in the development and treatment of psychiatric disorders has been extensively reviewed (Tsankova et al. 2007) as well as general features of cognition and behavior (Graff and Mansuy 2008; Levenson and Sweatt 2005; Sweatt 2009).
A total of 3236 independent two-hybrid interactions involving 1920 proteins (52% of the total protein coding genes) were identified and each interaction was evaluated using an interaction generality (IG) measure, as well as the general features of interacting partners.
Therefore, our results cannot be interpreted as a general feature of all cis-regulatory regions, but as a specific feature of proximal promoters.
