As apoptosis required no further stimulation to proceed, we revealed an unanticipated oncogenic role for PON2, apparently of special importance for leukemias or lung cancer.
Although we could not test the recovery of IFN-α production capability by pDCs purified from SLE patients, the PBMCs from SLE patients recovered IFN-α production capability over time in vitro, without further stimulation, as shown in Additional file 1 (Supplementary Figure 2).
This time span, called working memory span, is defined as the time a synchronous firing in the neurons that are stimulated is sustained without further stimulation.
Vinblastine, another microtubule depolimerizing agent, did induce tendril coiling in Pisum without further stimulation.
Consequently, the SciGas only detected concentrated gases, which degass readily without further stimulation.
Further, stimulation of neuro- and gliogenesis, synaptogenesis, neurite outgrowth, and also immunomodulation are crucial.
Without any further stimulation, cementum-like material will spontaneously repair the damage within 2 3 weeks.
Therefore, in addition to acting as an antigen source, the injected DCs may also cause activation of endogenous recipient DCs without further stimulation.
For the sham stimulation (control) condition, the sponge electrodes were placed in the same positions as in active stimulation, but after 30 seconds, the electrical current was covertly ramped down so that subjects did not receive further stimulation for the rest of the experiment.
This leads to the consumption of ATP and the generation of ADP, stimulation of phosphofructokinase, further stimulation of glycolysis, and subsequent production of pyruvate that is converted into lactate by pyruvatdehydrogenase. Consequently, the increase in blood glucose and lactate levels may be regarded as a metabolic response to adrenaline stimulation [ 6].
