Beyond insect locomotion our approach may well be applied to other areas of quantitative behavioural analysis, as, for example, for characterising the influence of genetic modifications [3], [4] or of drug treatment on behaviour [9], [16].
Opposite regulation was also observed with a few genes between the donors, as, for example, for PDK4, which was up-regulated in donors #1 and #2 but down-regulated in donors #3 and #4 after treatment with 5 µM and 20 µM TRO.
Noteworthy, it must be borne in mind that, in addition to limited qualitative differences in the gene sets deregulated by the two classes of agonists, major quantitative differences between ROSI and MURA at a 50 µM concentration were sometimes observed, as, for example, for PDK4, FGF21 and PLIN genes.
In case of many negatively charged groups as, for example, for double sulfated GlcUA or IdoUA, these positions could be not unique.
Our focus on Aβ-derived peptides may miss structural contributions like hydrogen-bond ladders, as, for example, for in-parallel stacked Asn or Gln, which also greatly enhances the stability of a parallel orientation.
This is supported by the appearance of the filaments in the electron microscopy images, where they look like beads on a string, which would not be expected if subunits were staggered in a double filament (as, for example, for actin and ParM).
A restricted progenitor can, for other malignancies, act as the initiating cell, as reported, for example, for BRCA1-associated breast cancers [ 39, 40].
Many TBP-enriched regions colocalize with H3K4me3 enriched regions as is seen for example for tubulin alpha 1c (Figure 4A; left panel).
This comparison was seen as useful, for example, for understanding how the availability of specialized services such as ophthalmology impacted on retinopathy screening.
In addition to food and beverage cans (bodies and ends) along with metal lids (closures) used on glass jars and bottles, the assessment of exposure here also covers aerosol cans (as used, for example, for cream and desert toppings) and collapsible metal tubes (as used, for example, for tomato paste, mayonnaise, mustard, some fish products, etc).
Experts do not expect high-speed connections to become as widespread as cable television, for example, for at least 20 years.
