The phrase "as first applied" is correct and usable in written English.
It can be used to refer to the initial application or implementation of a concept, method, or rule.
Example: "The results of the experiment were consistent with the theory as first applied in the original study."
Alternatives: "as initially implemented" or "as originally applied".
We employed iterative mathematics, as first applied by West [ 4], and the algorithms developed by Giovannini and coworkers [ 10] allow modelling of carbon dioxide exchange with particular precision.
In the case of mixture models a popular choice of algorithm is the Expectation Maximization (EM) algorithm, as first applied to this model and expressed sequence tag data by Xing et al. (2006) and later to RNA-seq data by Li et al. (2010).
Background subtraction (BS) is a crucial step in many computer vision systems, as it is first applied to detect moving objects within a video stream.
As early as 1970, Aspberg and Lloyd first applied lectin affinity for enrichment of glycosylated-proteins [ 12, 13].
But even if one did work when first applied, as its level of concentration dropped, bacteria could produce strains that resist it.
In order to alter specific locations on a wafer, a photoresist layer is first applied (as described in the section Deposition).
The SCORPAN models were first applied as standalone trend models and next extended with a component accounting for the spatial autocorrelation of the residuals from the trend.
Suitably selected ionic liquids (ILs) are first applied as antistatic agents for poly methyl methacrylate) (PMMA) and poly(butyl methacrylate) (PBMA) films in this study.
Metakaolin-based geopolymers, which were first applied as structural separators in this paper, were prepared with metakaolin and different moduli of alkaline activator solution.
By the 14th century the Peloponnese was known as the Morea (Mulberry), first applied to Elis, a northwestern mulberry-growing district, and it was the site of the Despotate of Morea.
Symmetrical uncertainty ranking [28] was first applied as an univariate criterion to measure the worth of each probe set alone: this computes the mutual information with respect to the class phenotype and compensates for the bias of the information gain.
