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By using a whole rat embryo culture model system, several biochemical processes have been examined, either as potential initial sites of teratogenic action or as early steps in the pathway to malformation.
Folate substrate inhibition probably evolved as a buffering mechanism against seasonal variation in folate availability from fresh leafy greens in order to maintain critical reactions in the folate cycle, such as early steps in the synthesis of purines and pyrimidines for DNA synthesis.
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Programs that were previously "added on" by the legislators to the county executive's budget, as Early Step Forward was, are automatically eliminated for the next year.
For this reason, they have been proposed as the early steps in a biological continuum toward breast cancer.
Proliferation, apoptosis, migration and invasion of the cells are referred to as critical early steps for lymphangiogenesis [ 23, 25, 31, 43].
As opposite, only fuzzy clues are known as to the early steps that trigger the DV gene regulatory network.
The decision by Parliament's Accountability and Justice Committee could be ratified by Iraq's electoral commission as early as Sunday, a step seen as a formality.
Consistent with results published by Malim and colleagues [12], [13], our recent work suggests that HIV-1 Gag assembly is regulated at a step as early as nuclear export of its encoding mRNA [14].
NPM1 loss may have occurred as an early step in MDS/AML as it remained stably mono-allelic in 4 NPM1+/− patients and did not develop in 6 NPM1+/+ over a median of 9 months follow-up (range: 2 156 months) (Table 2).
Tetraploidy is commonly seen in human cancer, including GLI2ΔN-driven malignancies, such as BCCs, and has been reported as an early step in human tumorigenesis and a contributing factor in the generation of aneuploid tumors.
That would suggest that his successor, who could be named as early as this week, would immediately step in to run the government.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com