The phrase "as disease progresses" is correct and usable in written English.
It can be used in medical or health-related contexts to describe changes or developments that occur as a disease advances over time.
Example: "As disease progresses, patients may experience a range of symptoms that can affect their quality of life."
Alternatives: "as the illness advances" or "as the condition worsens".
Perhaps the most significant differences between the Syrian hamster and Turkish hamster HPS models are the discordance in fatality rates and the observation that Turkish hamsters infected with LNV progressively lose weight as disease progresses whereas the weight of Syrian hamsters infected with ANDV remains steady or increases.
In disease, progressive hyperphosphorylation of tau, in particular at pathologic sites, such as pS422 occurs as disease progresses, concomitant with NFT formation [6].
These systems have the advantage of controlling local dosing so that payload is released at a time and with a dose chosen by a physician or patient, and the dose can be varied as disease progresses or healing occurs.
With dozens of novel drugs in development, there is more need than ever to develop biomarkers that distinguish normal aging from AD and AD from other dementias, track changes over time as disease progresses, and respond to interventions.
Why might HLA associations become weaker as disease progresses?
TB in cattle is characterized by an early Th1 type CMI response, whilst humoral immune responses develop as disease progresses.
As disease progresses, mesangial proliferation, endocapilliary proliferation, vascular collapse and immune complex accumulation in kidney result in glomerulonephritis and eventual renal failure [3],[4].
They have been shown to suppress HIV-specific T cell responses [47] but on the other hand their numbers decline as disease progresses [48].
Nevertheless, the very gradual increase in levels of N-terminally truncated Aβ as disease progresses implies that amide hydrolysis occurs infrequently and as such only an exceedingly small rate constant would be required.
Notably, increasing evidence indicates that BACE1 levels become elevated in AD brains as disease progresses; however, it remains unclear how the BACE1 upregulation may affect efficacies of therapeutic interventions including BACE1-inhibiting approaches.
In RA, immature vessels seem to appear relatively early in the disease but as disease progresses their density increases, being maximal in long-standing, active, and erosive disease groups.
