The phrase "as demonstrated by a significant decrease" is correct and usable in written English.
You can use it when you want to indicate that evidence or proof of something is shown through a notable reduction in a particular metric or variable.
Example: "The effectiveness of the new policy is evident, as demonstrated by a significant decrease in employee turnover rates."
Alternatives: "as evidenced by a notable reduction" or "as shown by a marked decline."
Analysis of the pancreatic lymph node demonstrated a striking reduction in transferred islet-reactive cells in the cSN50- treated mice, as demonstrated by a significant decrease in the absolute number of CFSE-labeled, Vβ4+ cells recovered at the end of treatment.
PKC δ knockdown cells displayed a protection towards oxLDL-induced apoptosis as demonstrated by a significant decrease in cell death.
This differs with effects of EOAH at lower doses in the TST as demonstrated by a significant decrease in depression-like behaviors.
When SB203580 was co-incubated with EMD protein, degradation of gelatin was stopped, as demonstrated by a significant decrease in specific fluorescent signals (panels G, H, I in Figure 5).
Immunization with either NE + rF-ptn or NE + RSV resulted in immunity characterized by enhanced viral clearance (Fig. 4A), as demonstrated by a significant decrease in lung mRNA expression of RSV proteins F and G when compared with sham vaccinated animals (P < 0.01).
There was a significant decrease in traffic from the flagellar pocket as demonstrated by a significant reduction (∼80%) in the uptake of tomato lectin in the induced cells.
Immediately following acetic acid injection, animals displayed a significant decrease in activity as demonstrated by a decrease in the number of contacts (F2,31 = 26.96, *P < 0.001) and rearing duration (F2,31 = 13.79, *P < 0.001).
The HIF-1 α deficient mice also had much less sepsis-associated tissue damage in different organs as demonstrated by an e.g. significant decrease in levels of liver enzymes (Fig. 1D).
As the treatment time was increased, DNA synthesis in NB4 cells became increasingly repressed as demonstrated by the significant decrease in the proportion of FITC-positive cells.
In this study, GR89,696 doses ≥ 1.25 × 10-3 mg/kg produced behavioral impairment (Fig. 2A, B), as demonstrated by the significant decrease in both rearing number and duration.
Furthermore, both systemic injections of fluoxetine and pirenzepine 1 h prior to the training session significantly reduced anxiety levels as demonstrated by a decrease in burying behavior.
