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We also integrated Gene Expression Omnibus (GEO) [ 18] to our system as database cross-reference.
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The primary keys in the evidence files are the BioDEAL Database Reference fields discussed in the Results section, with the Locus_tag field serving as the database cross-reference purpose.
In the case of BindingDB and DrugBank we used the UniProtKB/Swiss-Prot database cross-reference for the protein counts rather than figures from the websites as this enabled the additional restriction to human proteins.
We imported subcellular localization annotations from comments and database cross-reference fields of UniProtKB.
At present, biological databases cross-reference other databases with accession numbers or IDs as one way of linking their related knowledge together.
In addition, the BRENDA (23) ontology is specified as the defining source for the enzyme by the database cross reference ('dbxref') (BRENDA 3.4.21.37).
For example, REACTOME cross-references UniProt, ChEBI, and Gene Ontology (GO); the PRIDE database cross-references UniProt and many other protein databases; and the Expression Atlas cross-references Ensembl genes, UniProt, and GO.
The third tab contains the publication data, including external database cross-references.
RINGdb also integrates organized database cross-references to allow users direct access to detailed information.
For each RGS protein and GPCR, database cross-references are provided.
Inside the obo file one can also reference terms defined in other ontologies by using database cross reference ("dbxref") lists.
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