The 'obvious influences' that are currently dominating the agenda that were discounted as core factors, as they are unlikely to be the dominant factors influencing differentiation in the development of the sector beyond 2025, are digitalization/ICT, internationalisation and the impact of demographic trends.
This clearly reveals that these two families of enzymes work as core factors and that GHF10, 11 and 45 help these core factors for the efficient cellulose degradation of the lower termite.
This result indicates that these three genes may serve as core factors in the control of catechin biosynthesis in tea plants regardless of the harvest season.
Willis-Shattuck et al. [ 15] conducted a systematic review on motivation and retention in LMICs and identified monetary and non-monetary incentives as core factors affecting motivation and retention in these countries.
The four factors extracted from the factor analysis were interpreted, according to the nature of the symptoms in each factor, as: core depressive factor (Factor I), cognitive factor (Factor II), anxiety factor (Factor III) and somatic factor (Factor IV).
Deficits in working memory have been identified as potential core factors in the development of ADHD, and anxiety is also a frequently associated condition.
In ESCs, some groups have used new methods for global target mapping to predict the target genes regulated by Oct4, Sox2, and Nanog, and these studies revealed the combinatorial occupancy of target gene promoters by these core factors, as well as both autoregulatory and feed-forward transcriptional circuits [ 16- 20].
Finally, Ago1 might process certain miRNAs in a manner independent of the other core factors, as has been found for its mammalian ortholog Ago2 (Cheloufi et al. 2010; Cifuentes et al. 2010).
Krüppel-like factors serve as core transcription factors and participate in regulation of numerous mammalian genes (Bieker, 2001; Black et al, 2001).
Genetic studies have established the role of Oct4 (Nichols et al., 1998), Sox2 (Avilion et al., 2003), Nanog (Chambers et al., 2003; Mitsui et al., 2003) and Esrrb (Festuccia et al., 2012) as the signature core factors in the pluripotency transcriptional network of mESCs (Chen et al., 2008; Loh et al., 2006; Marson et al., 2008).
Surprisingly, during the pluripotent state, the top important miRNAs do not directly regulate the pluripotent core factors as previously thought, but they only directly target the pluripotent signal pathways and directly repress developmental processes.
