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In the kappa locus, in particular, many IGKV2 family members share specific parts of coding regions, such as complementary determining region 1, between genes but not between alleles.
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The antigen binding site, present on the upper tips of the Y shape, is formed by six hypervariable (HV) loops also referred to as the complementary determining regions (CDRs).
Next, Savage and colleagues immobilized their capture antibody (19.3, a humanized antibody with the same complementary determining regions as 3B3) on magnetic beads and detected with mAb 82E1 (an N-terminal specific mAb, like 3D6).
Accordingly, we decided to try this platform first using a new oAβ-specific monoclonal antibody we generated and then employing the antibodies with the same complementary determining regions as those used by Savage and colleagues [ 8].
complementary determining region 3. recombination signal sequence.
Furthermore DIC and DSPC work as complementary techniques to determined the micro and macromechanical behavior of the CuAlBe shape memory alloy.
As much as determined.
Additionally, several biochemical responses (metallothionein, 7-ethoxyresorufin O-deethylase, vitellogenin) were determined as complementary tools.
These nitrogen-containing bases occur in complementary pairs as determined by their ability to form hydrogen bonds between them.
Further, we used IPAA as a complementary technique for determining elements: in particular, Pb, Tl and Zr which are difficult to determine by INAA, are important from toxicological and environmental point of view.
The authors suggested the blood/VH concentration ratio as a "complementary tool" for determining intake-to-death time, without giving further details of how it could be used.
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