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Mean total costs per patient were 20% lower in the on-demand group as compared with the planned group.
Their initial study found no significant differences in morbidity or mortality in the on-demand relaparotomy group as compared with the planned relaparotomy group.
As a consequence, although dose reductions of bevacizumab were never done and only one patient had a 50% reduction of dose of chemotherapy because of severe haematologic toxicity, median dose intensity of bevacizumab and of irinotecan (considered as indicative for all the cytotoxic drugs) was reduced as compared with the planned one: 69% (range 60 92) and 78% (range 45 98), respectively.
Similar(57)
The measured doses were compared with the planned ones.
As compared with the IMRT plan, the VMAT-S plan significantly reduced the irradiated volume of the OARs and NT receiving medium to high doses.
As compared with the IMRT plan, the VMAT-S plan provided a more homogeneous dose distribution in the PTV and better sparing of the OARs and NT in the medium to high dose region; a slightly larger volume of normal tissue received a radiation dose of 20 Gy.
The VMAT-S plan significantly improved the PTV dose homogeneity as compared with the IMRT plan.
They found that the mean dose (Dmean) of the left and right parotid glands increased by 2.6 ± 4.3% and 0.2 ± 4.0% and V26 increased by 3.5% ± 5.2% and 0.3% ± 4.7%, respectively, as compared with the initial plan.
Once these three treatment plans were applied, we were able to determine the ICERs for both the Treat All plan and the Treat Boundary Spanners plan as compared with the baseline treatment, which is Treat None.
According to the analysis by the Congressional Budget Office, the President's plan would save $602 billion over seven years, as compared with the $664 billion savings in the Republican budget plan that Congress approved in November and Mr. Clinton vetoed.
The primary analysis showed that planned cesarean delivery did not increase or decrease the risk of fetal/neonatal death or serious neonatal morbidity as compared with planned vaginal delivery.
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