The AEs up to 12.5 mg (16 18%) were described as being mild in the majority of patients whereas the AEs after 25 mg (25%) were described as being of moderate intensity in 48% of cases.
The severity of these two subjective symptoms was rated as being mild, moderate, severe, and very severe, although only around 1.4 3.3 % of the patients complained of severe and very severe hoarseness and pain in the extremities (see Fig. 5).
A finding in the present study was that intensity of headaches was positively related to frequency, i.e., students with daily or almost daily headaches also reported them to be severe, while those with low-frequent headaches experienced them as being mild.
The pain was categorized as being mild, moderate, or severe.
Disease severity was investigator-assessed and classified as being mild, moderate, or severe.
Criteria used for classifying patients as being mild, moderate or severe are defined in Table 1.
Respondents reporting pain rated the usual intensity of their pain or discomfort as being mild, moderate, or severe.
The histological changes were estimated semi-quantitatively, as being mild, moderate, or marked by microscopic examination of histological sections.
Regarding the HADS, those percentages of the sample classified as being mild, moderate or severe cases, as indicated by Snaith and Zigmond's criteria [ 26], are also presented.
Pain was regarded as being mild if it was not discomforting or prevent the patient from sleeping and did not require the prescription of analgesics.
Although these sprains were mostly described as being mild and leading to short term discomfort, they could be classified as subjective sensations of giving way.
