They argue that standard ethical justifications for awarding special funding status to orphan drugs are not based on "rarity" in itself but rather on other characteristics of orphan diseases, such as severity and no alternative treatment, that could just as easily be applied to common diseases.
I talked some about the definition of negligence as it is applied to common carriers, and about the unexpected, latter-day reshapings of general tort-law paradigms in the years since the Nixon appointments.
This article reviews the locking mechanism and design of the fixation screws and plate, and the details of the surgical technique including the double-tired subchondral support procedure as it is applied to common fractures.
As applied to the common people, wuwei poses an ethical challenge, which demands doing less of the many needless activities that cloud the heart-mind and corrupt one's nature, and in the end only serve to perpetuate the tyranny of desire.
This paper contrasts applications of both the contingent valuation (CV) and contingent ranking (CR) methods as applied to a common issue, the valuation of improvements to the water quality of an urban river (the River Tame, running through the city of Birmingham, UK).
These concerns even apply to common assays (such as KRAS and EGFR mutation detection and Ki-67 IHC) and may result in discordant results.
We have discussed the strategies for, and challenges associated with, the interpretation of noncoding putative enhancer SNPs as applied to the study of common variants identified by GWAS studies of common diseases and traits.
Much of the proposed legislation actually extends common-law benefits and obligations even further for heterosexuals -- for example, the provision preventing the transfer of money to a spouse shortly before bankruptcy, which now applies only to married couples, would apply to common-law couples as well.
The same rules as apply to it.
Nevertheless, the new green procedures, such as synthesis in water or under solvent-free conditions, applied to such common processes as, for example, proton abstraction from phosphonium salts or transformation of ylide precursors, offer new possibilities for target structure design.
