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Recently, SIRT7 was identified as another suppressor of MYC function.
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Decorin, which acts as a suppressor of cellular proliferation, is another EGFR binding matrikine.
Another interesting enzyme that was isolated as a suppressor of position effect variegation is the dual kinase JIL-1/SU VAR 3-1 JIL-1/SU VAR 3-1
Another study using C. elegans (20) identified Hsp90 as a suppressor of WT α-syn toxicity; we identified the same gene.
The prospect of boosted foetal haemoglobin levels in patients was helped when it was found that a gene called BCL11A acts as a suppressor of foetal haemoglobin production.
This study provides the first evidence for HSF2 acting as a suppressor of invasion in human malignancies.
Through a genome-wide genetic screen, we identified DEAD-box helicase 6 (DDX6) as a suppressor of ISGs.
Arginine is widely used as aggregation suppressor of proteins in biotechnology and pharmaceutics.
These data establish Lgl1 as a suppressor of gliomagenesis and positive regulator of asymmetric division and differentiation in the healthy and demyelinated murine brain.
Williamson L, Raess NA, Caldelari R, Zakher A, de Bruin A, Posthaus H et al. Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.
We propose a model in which HSF2 functions as a suppressor of EMT, tumor plasticity and invasion in tumorigenesis (Figure 10).
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