Sentence examples for as an inflammatory factor from inspiring English sources

As an inflammatory factor, MIF also plays a role of inflammatory mediators in various diseases.

Using a cross-sectional design, 500 participants free from heart disease drawn from the Whitehall II study in UK in 2006 2008 were tested for plasma fibrinogen as an inflammatory factor, financial strain as a marker of chronic psychosocial stress, coronary calcification measured using computed tomography, and for plasma high-sensitivity cardiac troponin T (HS-CTnT) as a marker of cardiac risk.

However, it is important to note that PGs may have other role(s) besides as an inflammatory factor.

Early investigations into the role of resistin as an inflammatory factor demonstrated that LPS (lipopolysaccharide) up-regulated resistin expression in rat WAT, 3T3-L1 andpocytes and human monocytes [ 16].

We also examined the expression of TNF-α as an important inflammatory factor at mRNA and protein levels, which shows that a significant increase in aortic expression of TNF-α at both mRNA and protein levels in the aortic tunica media of diabetic mice without gender difference.

The presence of brain microglia has been implicated in rotenone neurotoxicity, and these cells release reactive oxygen species as well as inflammatory factors (Gao et al. 2002; Liu and Hong 2003).

ROS may also act as an inflammatory signaling factor mediated microglial activation induced by IL-1 β [ 39].

Whether Smad7 acts as an anti-inflammatory factor or as a pro-inflammatory factor varies with the context of the stimulating agent, microenvironment, tissue type, and disease model.

Alcohol can suppress the synthesis of proinflammatory cytokines and chemokines such as tumor necrosis factor and interleukin-6, in vivo or in vitro (or both) [ 44, 45], and it may also have a role as an anti-inflammatory factor.

Finally, because the effects of HMG1 and p8 seem to be opposite (e.g.: HMG1 play a pro-inflammatory role whereas p8 acts as an anti-inflammatory factor), we analyzed in detail expression of HMG1 mRNA by semiquantitative RT-PCR.

Our data indicate that PPARgamma plays a central role in the development of IR, acting as an anti-inflammatory factor on T-lymphocyte activation and infiltration into fat tissue, and by this mean contributing to the attenuation of the systemic development of IR.